Ex vivo high-definition optical coherence tomography of basal cell carcinoma compared to frozen-section histology in micrographic surgery: a pilot study. Maier T, Kulichova D, Ruzicka T, Kunte C, Berking C. Noninvasive monitoring of basal cell carcinomas treated with systemic hedgehog inhibitors: pseudocysts as a sign of tumor regression. Maier T, Kulichova D, Ruzicka T, Berking C. High-definition optical coherence tomography algorithm for discrimination of basal cell carcinoma from clinical BCC imitators and differentiation between common subtypes. 2015 172(4):1153–4.īoone MA, Suppa M, Pellacani G, Marneffe A, Miyamoto M, Alarcon I, et al. Three-dimensional high-definition optical coherence tomography image acquisition procedure for basal cell carcinoma. 2012 167(4):856–64.īoone M, Suppa M, Miyamoto M, Marneffe A, Jemec GB, Pellacani G, et al. Imaging of basal cell carcinoma by high-definition optical coherence tomography: histomorphological correlation. High-definition optical coherence tomography enables visualization of individual cells in healthy skin: comparison to reflectance confocal microscopy. High-definition optical coherence tomography: presentation of the technique and applications in dermatology. Marneffe A, Suppa M, Miyamoto M, Del Marmol V, Boone M. Histomorphologic correlation with routine histology and optical coherence tomography. 1997 37(6):958–63.īechara FG, Gambichler T, Stucker M, Orlikov A, Rotterdam S, Altmeyer P, et al. Optical coherence tomography of the human skin. Welzel J, Lankenau E, Birngruber R, Engelhardt R. Imaging caries lesions and lesion progression with polarization sensitive optical coherence tomography. 2003 19(2):171–8.įried D, Xie J, Shafi S, Featherstone JD, Breunig TM, Le C. Guidance of aortic ablation using optical coherence tomography. Patel NA, Li X, Stamper DL, Fujimoto JG, Brezinski ME. Comprehensive esophageal microscopy by using optical frequency-domain imaging (with video). Vakoc BJ, Shishko M, Yun SH, Oh WY, Suter MJ, Desjardins AE, et al. High-resolution imaging of the human esophagus and stomach in vivo using optical coherence tomography. Optical biopsy and imaging using optical coherence tomography. 2007 49(13):1474–81.įujimoto JG, Brezinski ME, Tearney GJ, Boppart SA, Bouma B, Hee MR, et al. Measurement of collagen and smooth muscle cell content in atherosclerotic plaques using polarization-sensitive optical coherence tomography. Nadkarni SK, Pierce MC, Park BH, de Boer JF, Whittaker P, Bouma BE, et al. Huang D, Swanson EA, Lin CP, Schuman JS, Stinson WG, Chang W, et al. High-definition optical coherence tomography.Given its ability to provide images on the vertical plane and to reach deeper into the dermis, HD-OCT appears as an ideal candidate to complement confocal microscopy in specialized dermatological centres. The possibility of examining the skin in the vertical plane has led to a particular interest for HD-OCT in non-melanoma skin cancer, as the diagnosis of both basal and squamous cell carcinoma is mainly based on features that are better seen in the vertical rather than horizontal plane. A good correlation has been found between HD-OCT and histopathological images in different areas of dermatology. HD-OCT horizontal images are better suited to evaluate the global architecture of the epidermis and of the papillary dermis (dermal papillae). HD-OCT vertical images allow the examination of the global architecture of the skin and the visualization of its different layers, namely epidermis and dermis, separated by the dermal–epidermal junction. It features a high isotropic resolution of 3 μm-thus allowing the visualization of individual cells-as well as an extremely quick generation of three-dimensional (3D) images up to a skin depth of 570 μm. High-definition optical coherence tomography (HD-OCT) is a non-invasive imaging technique based on the physical principle of interferometry.
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